1. Brains create pain; pain is not a native property of the things with which you traditionally associate it. If you're suffering, it's because your brain is a painful organ -- not because the stimulus affecting your neurological wiring is actually painful. Brains hurt.
2. Furthermore, brains create and poorly manage bad memes -- which, like the genes necessary for brains to exist at all, get passed on from generation to generation in the interest of staving off entropy. Brains are selfish and illogical.
3. The universe would be absolutely devoid of value if it weren't for the existence of sensation; even bacteria, which dominated the first three billion years of evolution of life on Earth, would be acceptable in a valueless universe, in no way compromising its neutrality. Prior to the beginnings of neurological functioning on Earth some billion years ago, it's possible that the universe wasn't the horror that some now think it to be; likewise, it's possible that it won't always be as horrible a place as it currently is. Brains are the worst, and thus most important, aspect of the universe.